Question 1
NSG-530-IKD Advanced Pathophysiology EXAM2. Which of the following is a potential sign of opioid overdose?
- Respiratory depression
- Hypertension
- Tachycardia
- Hyperglycemia
Question 2
The REMS (Risk Evaluation and Mitigation Strategy) for extended-release and long-acting opioids requires prescribers to:
- Perform genetic testing
- Complete opioid safety training
- Avoid prescribing opioids altogether
- Prescribe naloxone to all patients
Question 3
What is a common adverse effect limiting opioid use?
- Hypertension
- Constipation
- Hyperglycemia
- Tachycardia
Question 4
What is an important consideration when prescribing opioids to elderly patients?
- Elderly patients metabolize opioids faster despite age related decline in organ function
- Increased risk of sedation and falls
- Opioids are contraindicated
- No dose adjustments needed
Question 5
Which opioid is known for having a ceiling effect on respiratory depression, making it safer in overdose situations?
- Morphine
- Fentanyl
- Buprenorphine
- Hydromorphone
Question 6
What is the role of naloxone in opioid overdose management?
- Long-term pain relief
- Reverse opioid-induced respiratory depression
- Enhance opioid analgesic effect
- Prevent opioid tolerance
Question 7
When converting from oral morphine to transdermal fentanyl, what is important to remember?
- Fentanyl patches have an immediate onset of action when applied
- Patients must be opioid tolerant
- Fentanyl patches are not for chronic pain
- Heating pad should be applied over the fentanyl patch for enhanced analgesia
Question 8
Which opioid is most likely to cause histamine release leading to pruritus and hypotension?
- Morphine
- Fentanyl
- Buprenorphine
- Oxycodone
Question 9
What is a major limitation of using tramadol as an opioid analgesic?
- Lack of serotonin effects
- Risk of seizure
- No oral formulation
- No analgesic effect
Question 10
Which opioid analgesic has intrinsic NMDA receptor antagonist activity, potentially reducing tolerance? NSG-530-IKD Advanced Pathophysiology EXAM2
- Methadone
- Codeine
- Hydrocodone
- Morphine
Question 11
What counseling point is important for patients starting opioids?
- Opioids will not cause sedation
- Avoid operating heavy machinery until you know how opioids affect you
- Do not take with any food
- Opioids do not cause constipation
Question 12
What is an important counseling point regarding storage of opioid medications?
- Store in unlocked, accessible place
- Keep out of reach of children and others
- Share with family members as needed
- Dispose only when expired NSG-530-IKD Advanced Pathophysiology EXAM2
Question 13
Which opioid is preferred for cough suppression rather than analgesia?
- Codeine
- Morphine
- Fentanyl
- Methadone
Question 14
According to the CDC opioid prescribing guidelines, what is the recommended maximum daily morphine milligram equivalent (MME) dose threshold to reduce overdose risk?
- 20 MME/day
- 50 MME/day
- 90 MME/day
- 120 MME/day
Question 15
According to CDC guidelines, how often should clinicians evaluate benefits and harms when prescribing opioids for chronic pain?
- Every day
- Every 3 months
- Every 6 months
- Every year
Question 16
Which of the following is a risk mitigation strategy recommended by the CDC when initiating opioid therapy?
- Avoid urine drug testing
- Start at high opioid doses for severe pain
- Discuss risks and benefits with patients
- Prescribe opioids without a treatment plan
Question 17
Which of the following is NOT an FDA-approved indication for buprenorphine?
- Opioid use disorder treatment
- Chronic pain management
- Acute postoperative pain
- Opioid overdose reversal
Question 18
What is the main concern with concomitant use of benzodiazepines and opioids?
- Increased analgesia
- Increased risk of respiratory depression
- Decreased opioid effectiveness
- Decreased benzodiazepine metabolism
Question 19
Which opioid is associated with a long half-life leading to accumulation, QTc prolongation and risk of overdose if dosed improperly?
- Methadone
- Morphine
- Hydrocodone
- Oxycodone
Question 20
What monitoring tool is recommended to assess risk of opioid misuse?
- Pain scale
- Opioid Risk Tool (ORT)
- Liver function tests
- The Palliative care Outcome Scale (POS)
Question 21
What is a primary reason for limiting opioid duration in acute pain according to CDC guidelines?
- Risk of addiction increases with duration
- Opioids have no analgesic effect after 3 days
- Patients become resistant in a short period of time
- No evidence supports opioid use beyond 1-2 days
Question 22
Which opioid has active metabolites that can cause neurotoxicity at high doses?
- Hydrocodone
- Meperidine
- Oxycodone
- Fentanyl
Question 23
Which opioid is preferred for patients with renal impairment due to its inactive metabolites?
- Morphine
- Oxycodone
- Fentanyl
- Meperidine NSG-530-IKD Advanced Pathophysiology EXAM2
Question 24
What is a contraindication to opioid therapy?
- Pregnancy with opioid use disorder under treatment
- Acute respiratory depression without ventilation support
- Mild pain
- Chronic non-cancer pain
Question 25
NSG-530-IKD Advanced Pathophysiology EXAM2. Which opioid receptor is primarily responsible for the analgesic effects of most opioid drugs?
- Delta (delta)
- Kappa (kappa)
- Mu (mu)
- Nociceptin
