NSG-530-IKD Advanced Pathophysiology EXAM2

Question 1

NSG-530-IKD Advanced Pathophysiology EXAM2. Which of the following is a potential sign of opioid overdose?

• Respiratory depression
• Hypertension
• Tachycardia
• Hyperglycemia

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Question 2

The REMS (Risk Evaluation and Mitigation Strategy) for extended-release and long-acting opioids requires prescribers to:

• Perform genetic testing
• Complete opioid safety training
• Avoid prescribing opioids altogether
• Prescribe naloxone to all patients

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Question 3

What is a common adverse effect limiting opioid use?

• Hypertension
• Constipation
• Hyperglycemia
• Tachycardia

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Question 4

What is an important consideration when prescribing opioids to elderly patients?

• Elderly patients metabolize opioids faster despite age related decline in organ function
• Increased risk of sedation and falls
• Opioids are contraindicated
• No dose adjustments needed

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Question 5

Which opioid is known for having a ceiling effect on respiratory depression, making it safer in overdose situations?

• Morphine
• Fentanyl
• Buprenorphine
• Hydromorphone

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Question 6

What is the role of naloxone in opioid overdose management?

• Long-term pain relief
• Reverse opioid-induced respiratory depression
• Enhance opioid analgesic effect
• Prevent opioid tolerance

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Question 7

When converting from oral morphine to transdermal fentanyl, what is important to remember?

• Fentanyl patches have an immediate onset of action when applied
• Patients must be opioid tolerant
• Fentanyl patches are not for chronic pain
• Heating pad should be applied over the fentanyl patch for enhanced analgesia

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Question 8

Which opioid is most likely to cause histamine release leading to pruritus and hypotension?

• Morphine
• Fentanyl
• Buprenorphine
• Oxycodone

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Question 9

What is a major limitation of using tramadol as an opioid analgesic?

• Lack of serotonin effects
• Risk of seizure
• No oral formulation
• No analgesic effect

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Question 10

Which opioid analgesic has intrinsic NMDA receptor antagonist activity, potentially reducing tolerance? NSG-530-IKD Advanced Pathophysiology EXAM2

• Methadone
• Codeine
• Hydrocodone
• Morphine

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Question 11

What counseling point is important for patients starting opioids?

• Opioids will not cause sedation
• Avoid operating heavy machinery until you know how opioids affect you
• Do not take with any food
• Opioids do not cause constipation

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Question 12

What is an important counseling point regarding storage of opioid medications?

• Store in unlocked, accessible place
• Keep out of reach of children and others
• Share with family members as needed
• Dispose only when expired NSG-530-IKD Advanced Pathophysiology EXAM2

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Question 13

Which opioid is preferred for cough suppression rather than analgesia?

• Codeine
• Morphine
• Fentanyl
• Methadone

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Question 14

According to the CDC opioid prescribing guidelines, what is the recommended maximum daily morphine milligram equivalent (MME) dose threshold to reduce overdose risk?

• 20 MME/day
• 50 MME/day
• 90 MME/day
• 120 MME/day

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Question 15

According to CDC guidelines, how often should clinicians evaluate benefits and harms when prescribing opioids for chronic pain?

• Every day
• Every 3 months
• Every 6 months
• Every year

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Question 16

Which of the following is a risk mitigation strategy recommended by the CDC when initiating opioid therapy?

• Avoid urine drug testing
• Start at high opioid doses for severe pain
• Discuss risks and benefits with patients
• Prescribe opioids without a treatment plan

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Question 17

Which of the following is NOT an FDA-approved indication for buprenorphine?

• Opioid use disorder treatment
• Chronic pain management
• Acute postoperative pain
• Opioid overdose reversal

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Question 18

What is the main concern with concomitant use of benzodiazepines and opioids?

• Increased analgesia
• Increased risk of respiratory depression
• Decreased opioid effectiveness
• Decreased benzodiazepine metabolism

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Question 19

Which opioid is associated with a long half-life leading to accumulation, QTc prolongation and risk of overdose if dosed improperly?

• Methadone
• Morphine
• Hydrocodone
• Oxycodone

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Question 20

What monitoring tool is recommended to assess risk of opioid misuse?

• Pain scale
• Opioid Risk Tool (ORT)
• Liver function tests
• The Palliative care Outcome Scale (POS)

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Question 21

What is a primary reason for limiting opioid duration in acute pain according to CDC guidelines?

• Risk of addiction increases with duration
• Opioids have no analgesic effect after 3 days
• Patients become resistant in a short period of time
• No evidence supports opioid use beyond 1-2 days

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Question 22

Which opioid has active metabolites that can cause neurotoxicity at high doses?

• Hydrocodone
• Meperidine
• Oxycodone
• Fentanyl

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Question 23

Which opioid is preferred for patients with renal impairment due to its inactive metabolites?

• Morphine
• Oxycodone
• Fentanyl
• Meperidine NSG-530-IKD Advanced Pathophysiology EXAM2

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Question 24

What is a contraindication to opioid therapy?

• Pregnancy with opioid use disorder under treatment
• Acute respiratory depression without ventilation support
• Mild pain
• Chronic non-cancer pain

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Question 25

NSG-530-IKD Advanced Pathophysiology EXAM2. Which opioid receptor is primarily responsible for the analgesic effects of most opioid drugs?

• Delta (delta)
• Kappa (kappa)
• Mu (mu)
• Nociceptin